D-Xylose, O-β-D-xylopyranosyl-(1→4)-O-β-D-xylopyranosyl-(1→4)-
Xylotriose
CAS: 47592-59-6
Molecular Formula: C15H26O13
D-Xylose, O-β-D-xylopyranosyl-(1→4)-O-β-D-xylopyranosyl-(1→4)- - Names and Identifiers
D-Xylose, O-β-D-xylopyranosyl-(1→4)-O-β-D-xylopyranosyl-(1→4)- - Physico-chemical Properties
| Molecular Formula | C15H26O13 |
| Molar Mass | 414.36 |
| Density | 1.68±0.1 g/cm3(Predicted) |
| Melting Point | 204-206°C |
| Boling Point | 767.6±60.0 °C(Predicted) |
| Specific Rotation(α) | -38.2 º (c=0.5% in H2O);-48 º (c=1% in H2O) |
| Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
| Appearance | White powder |
| Color | White to Off-White |
| pKa | 12.40±0.20(Predicted) |
| Storage Condition | Hygroscopic, Refrigerator, Under inert atmosphere |
| Stability | Hygroscopic |
| MDL | MFCD00057525 |
D-Xylose, O-β-D-xylopyranosyl-(1→4)-O-β-D-xylopyranosyl-(1→4)- - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| HS Code | 29400090 |
D-Xylose, O-β-D-xylopyranosyl-(1→4)-O-β-D-xylopyranosyl-(1→4)- - Reference
| Reference Show more | 1. Han Pengfei, Guo Jianzhong, Li Bing, etc. Optimization of process conditions for preparation of xylo-oligosaccharides from xylan catalyzed by solid acid [J]. Science and Technology of food industry, 2017. 2. Han Pengfei, Yu Zhusi, Guo Jianzhong, Li Bing, Liu Li. Optimization of preparation of xylo-oligosaccharides from xylan catalyzed by carbon-based solid acid [J]. Food Science, 2017,38(12):171-176. 3. [IF = 8.198] ABR Basit et al."High Efficiency Degradation of Xylan into Xylose by a Single Enzyme. Acs Sustain Chem Eng. 2019;7(13):11360-11368 4. [IF = 4.411] Zhao Jun Peng et al." Purification, Identification, and Characterization of an Endo-1,4-β-Xylanase from Wheat Malt."Molecules. 2020 Jan;25(7):1572 5. [IF = 5.645] Na Li et al."Improving catalytic efficiency of endoxylanase for degrading corncob xylan to produce xylooligosaccharides by fusing a β-xylosidase."Ind Crop Prod. 2022 Feb;176:114349 6. [IF=4.952] Jiapeng Wang et al."Efficient secretion of xylanase in Escherichia coli for production of prebiotic xylooligosaccharides."LWT-FOOD SCIENCE AND TECHNOLOGY. 2022 Jun;162:113481 |
D-Xylose, O-β-D-xylopyranosyl-(1→4)-O-β-D-xylopyranosyl-(1→4)- - Reference Information
| background and overview | xylan is the main component of hemicellulose, is a poly five carbon sugar, accounting for about 15%-35% of the dry weight of cells, and is the most abundant renewable resource in nature except cellulose. The structure of xylan is very complex, and the complete degradation of xylan requires the participation of multiple enzymes. Xylanase is widely distributed and abundant in nature. It exists in marine and terrestrial bacteria, marine algae, fungi, yeast, bacteria and ruminant rumen, snails, crustaceans, terrestrial plant tissues and various invertebrates. Among them, β-1,4 endoxylanase is the most important enzyme to degrade xylan, which acts on the main chain of xylan to generate oligosaccharides with different chain lengths. Xylo-oligosaccharide, also known as xylo-oligosaccharide, is an oligosaccharide formed by connecting 2~7 xylose with β(1 → 4) glycosidic bonds. The degree of polymerization of xylo-oligosaccharides is usually 2~7. It is a xylo-oligosaccharide mixture obtained by hydrolysis of xylan as a substrate with xylo-disaccharides and xylo-trisaccharides as the main components. The sweetness of xylo-oligosaccharides is about the 50% of sucrose, and the sweetness is pure, similar to sucrose. Xylo-oligosaccharides have a highly selective proliferation effect on bifidobacteria in the intestine, and play an important role in reducing cholesterol, maintaining intestinal health, and promoting calcium absorption. |
| physical and chemical properties | compared with other oligosaccharides, xylotriose has good stability, and there is no obvious change after heating for 1h in the range of pH2.5 ~ 8.0, while the stability of other oligosaccharides is much worse under this condition. This shows that xyltrisaccharide has good stability in a wide pH range (almost covering the pH of most food systems). 1% xyltriose aqueous solution was stored at 5 ℃, 20 ℃ and 37 ℃ for 3 months in the range of pH2.5 ~ 7.0, respectively, without obvious change. After storage at 37 ℃ for 2 months, the residual rates at pH2.5, pH7.0 and pH8.0 were 99.6%, 99.1% and 97.9% respectively. Further research shows that the beverage with pH3.4 is stored at room temperature for one year, and the retention amount of xyltrisaccharide reaches more than 97%. The physicochemical properties of xyltrisaccharide are very stable, have high stability to heat and acid, and have good storage stability at room temperature. These properties are extremely prominent in functional oligosaccharide products. When practical, there is no need to worry about the decomposition of active ingredients during processing. It is very convenient to use and can be used in various food systems. |
| pharmacokinetics | it is difficult to decompose by human digestive enzyme system. digestion tests with saliva, gastric juice, pancreatic juice and small intestinal juice show that almost all digestive juices can not decompose xylo-oligosaccharides, so its energy value is very low or zero. |
| preparation method | high purity xylaniose and xylanide were obtained by gel filtration chromatography: xylaniose and xylaniose were prepared and separated by using polyacrylamide gel (Bio- GelP-2) as chromatography medium, fast protein liquid chromatography (FPLC) system as platform, degassed high purity water elution, they were used as carbon sources to study the growth process of Bifidobacterium adolescence cultured in vitro. The specific steps are as follows: chromatographic separation of xylo-oligosaccharide mixed solution is carried out at an elution rate of 60 mL/h. Bio-GelP-2, multiple fractions can be obtained by separating xylo-oligosaccharide mixed solution. the results are as follows: peak 4 and peak 5 are xylaniose and xylanose components respectively. different fractions of peak 4 (4 fractions with elution volume of 772~782,782~792,792~802 and 802~812m L) and different fractions of peak 5 (elution volume of 722~732,732~742 and 742~752 mL of 3 fractions) were analyzed by HPLC respectively. The results show that xylodisaccharide is the main component in the grade of peak 4, with a content between 84.8% and 98.5%, and also contains a small amount of xylotriose, glucose or arabinose. Peak 5 is a component with xylosaccharide as the main component, with a content of 80.3% ~ 89.7%, and also contains a small amount of xylosaccharide and xylose. The peak 4 and peak 5 components collected many times were combined and concentrated. HPLC analysis results showed that the purity of xylaniose and xyletriose were 95.6% and 83.4% respectively. |
| main reference | [1] she yuanli et al. Identification of a Streptomyces strain with xylanase from high xylodisaccharide and xylotrisaccharide. Food industry technology. 2010,10:190-193. [2] Editor-in-Chief Zheng Jianxian. Low energy food. Beijing: China Light Industry Press. 2001. Page 147-148. [3] Zhang Junhua et al. Isolation of xylobiose and xylobiose and their application in vitro culture of Bifidobacterium. Forest chemistry and industry. 2005, 25(1):15-18. |
| biological activity | Xylotriose (1,4-b-D-Xylotriose, 1,4-beta-D-xylotriose) is a natural xylo-oligosaccharide substrate that can be hydrolyzed by catalytically effective β-D-xylosidase derived from Selenomonas ruminantium (SXA). |
Last Update：2024-04-09 19:05:03
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Product Name: Xylotriose Visit Supplier Webpage Request for quotationCAS: 47592-59-6
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QQ: 3008007409
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